FAQ

Psychobiotics are strictly defined strains of probiotic bacteria, i.e. beneficial and human-friendly microorganisms that have a positive effect on mental health. The term ‘psychobiotics’ was coined in 2013. Two scientists, psychiatrist Ted Dinan and neuroscientist John F. Cryan.

Psychobiotics have a positive effect on the gut-brain axis, the essence of which lies in the advanced neural, endocrine and immunological mechanisms of communication between the digestive system and the central nervous system-a two-way pathway that involves the vagus nerve and hormonal and immune mechanisms

Systemic psychobiotic 2 U not only restores healthy gut microbiota, it is simultaneously involved in the regulation of three systems:

Nervous- KE 2U is involved in the synthesis of neurotransmitters: serotonin, acetylcholine, GABA (gamma-aminobutyric acid)melatonin and histamine.Thus the bacteria are involved in the functioning of the so-called hypothalamic-pituitary-adrenal axis, which is crucial for the maintenance of mental health (especially in depression)

Endocrine- Reduces the concentration of the stress hormone cortisol. Immune- Increases the formation of anti-inflammatory cytokines. This fact is significant in light of discoveries linking chronic, generalised inflammation in the body to the onset of neurotic-anxiety disorders and neurodegenerative diseases.

Through the vagus nerve, neurotransmitters, cytokines and hormones, information from the gastrointestinal tract is constantly transmitted to the brain. However, it is important to realise that due to the bidirectional nature of the intestinal-brain pathway, there are also numerous depndencies with opposite vectors.

It is proven, among other things, that chronic stress has a negative effect (through the hormone cortisol) on the composition of the intestinal microflora, and indirectly on human immunity and many other vital processes.

The term microbiome was first coined in 2001 to refer to the collective community of microorganisms. The microbiome represents the entire diversity of bacteria that are found both inside and outside our bodies.

The term ‘microflora’ used to be used in this sense, but it has been abandoned. After all, ‘flora’ is the plant world, not the vast diversity of the microcosm of the human body.

A new era in the study of the intestinal microbiome came only 5-10 years ago and is associated with the emergence of molecular genetic methods of research. They overturned the ideas about the microcosm.

There came a completely new understanding of the necessity of the presence of friendly microorganisms in the human body not only for our digestion, but also for the body and health in general.

Today the human body is regarded as a complex superorganism. It is a symbiotic community of numerous eukaryotic, prokaryotic cells, including archaebacteria and viruses. It is abundantly populated by microorganisms numbering in the billions. The number of bacterial species ranges from 2.5 to 4 thousand, and strains - up to 70 thousand!

At the same time, the microcosm of each person is individual. The species composition is relatively stable in each of us. The total content of bacteria and the number of their species in different people can differ by 12 to 2200 times. Not only our set of chromosomes is unique, but also our set of microbiome.

The microbiota plays an important role in maintaining our health. The human microbiome is now considered as a single metabolically active organ. The microbiota and our body's mucous membranes are constantly interacting and mutually influencing each other.

One of the main functions of the microbiota is to build colonisation resistance. This is a mechanism on our mucous membranes that prevents ‘bad’, exogenous or external microorganisms from colonising and overgrowing. Nature does not tolerate emptiness. If the mucous membranes are tightly closed by normal healthy biofilms, these mucous membranes cannot ‘repopulate’ pathogenic bacteria. Normal microbiota will not let them in. This is an important defence mechanism.

Competition for attachment sites on mucous membranes and food sources. Competition for attachment to mucosal bacteria is fierce in the microbial world. There is a scientific term called adhesion. Before bacterial inflammation occurs, there must be adhesion or ‘sticking’ of pathogenic bacteria on a particular area of mucosa or skin. Our healthy microflora does not allow adhesion to occur.

Gas exchange. The microbiome is involved in the regulation of gas exchange in the gut and other body cavities.

Production of enzymes involved in the metabolism of proteins, fats, carbohydrates.

Detoxification. The normal healthy microbiota actively detoxify the body

Formation of free metabolites, formation of bile.

Increased resistance of epithelial cells to mutagens or carcinogens. Coming from the external or internal environment, mutgens are able to cause mutation on mucous membranes and, consequently, lead to the development of cancer. Preventing mutagens from affecting the mucosal cell is one of the functions of the microbiota. If the microbiota is of high quality, the mucosa will be protected, including from the effects of mutagens.

Carcinolytic function. If there is a breakdown in the genome of the cell, and it begins unrestrained growth, it means the formation of cancer. Normal microbiota producing its enzymes, interferons, will have a ‘stopping’ effect on the tumour.

Gene storage function. The microbiome is a giant repository of microbial, plasmid and chromosomal genes. Possible deletion, insertion of genes, ‘repair of broken’ genes occurs due to the presence of microbial plasmid repository. It turns out that the cells of the immune system, the cells that control genetic purity, always have material at hand to ‘patch’, ‘repair’ any failures in the human genome.

Absolutely yes, 2 U is recommended for the formation and maintenance of a healthy microbiota, which plays a key role in the prevention of various gastrointestinal diseases, allergies and other disorders. Maintaining the balance of a healthy microbiome promotes better digestion and reduces the likelihood of inflammatory diseases. In addition, the formation of a healthy microbiota has a positive effect on the immune system. Regular use of 2 U helps reduce the frequency and severity of infectious diseases, allergic reactions and inflammation.

In addition to improving the work of the gastrointestinal tract and immunity-healthy microbiota has a positive effect on the psycho-emotional state. The probiotics in Complex 2 U promote the production of metabolites that can affect serotonin and other neurotransmitters, which can ultimately improve mood, reduce anxiety and help fight depression.

Preventive use 2 U are beneficial for people of different ages. For children from the age of 3 and adolescents, the formation of a healthy microbiota contributes to proper physical and mental development. Adults may notice an improvement in the functioning of the GI tract, increased defence against infections and even a reduction in the manifestations of chronic diseases. Older people, who are at greater risk of immune and metabolic disorders, may also benefit from regular 2 U intake.

In a standard 2 U pack you will find two components: a stick - with dry selective microencapsulated biomass and a dark glass bottle - with liquid beccellular biofermented bacterial filtrate. THE TWO COMPONENTS DRY AND LIQUID SHOULD BE MIXED JUST BEFORE USE! It is better to mix/combine them in 100-150 ml pure water.

It is sufficient to take 1 time per day.

It is allowed to take 2U directly with meals, before meals, on an empty stomach and during the day. It is recommended to adjust the intake of 2U individually to your regime and subjective feelings.

The full course for stable results is 28 days. Thereafter, you can take it 2-3 times a week to continuously maintain a healthy gut microbiome and balanced functioning of the whole organism.

As a preventive course, it can be taken in courses of 10 days to 3 weeks, preferably twice a year. Taking preventive courses of 2U can significantly improve physical and mental health.

There are no side effects or contraindications when taking 2U. On the contrary, 2 U is an effective treatment for endogenous food allergies and is used in the complex treatment of many allergic conditions

At room temperature not exceeding +25C, avoid direct sunlight. Shelf life 18 months.

BUT! It is better to store in the refrigerator at +2-+4, which will significantly extend the period up to 2.5 years.

Yes, it is compatible. Taking 2U will help to mitigate and minimise the detrimental effect of alcohol on the beneficial intestinal microflora, as well as contribute to the rapid elimination of toxins from the body.